PANTHER

Protein analysis through evolutionary relationships (PANTHER)

Classifies genes by their functions, using published scientific experimental evidence and evolutionary relationships to predict function even in the absence of direct experimental evidence. Proteins are classified by expert biologists into families and subfamilies of shared function, which are then categorized by molecular function and biological process ontology terms. PANTHER includes "PANTHER Genes" (genes, transcripts and proteins in Human, Mouse, Rat, and Drosophila melanogaster), PANTHER Families (Protein families and subfamilies and associated data such as phylogenetic trees, multiple sequence alignments and HMMs), "PANTHER Pathways" (expert-curated signaling and metabolic pathways mapped to protein sequences in PANTHER Library) and "PANTHER Ontologies".

ID	PANTHER
Acc	DB-0069
Home	http://www.pantherdb.org/
EDAM topic	Pathways, networks and models
EDAM topic	Protein families
EDAM topic	Gene family or system
EDAM topic	Phylogenetics
Category	Family and domain databases
Category	Protein sequence classification database
Taxon	all

Available data

Data	Format	Query	Link
Protein family annotation {PANTHER Family}	HTML	Protein family ID (PANTHER)	http://www.pantherdb.org/panther/family.do?clsAccession=%s
Pathway or network report	HTML	Pathway ID (Panther)	http://www.pantherdb.org/pathway/pathwayDiagram.jsp?catAccession=%s

Example queries

Data	Format	Query	Example
Protein family annotation {PANTHER Family}	HTML	Protein family ID (PANTHER)	PTHR12649:SF6
Pathway or network report	HTML	Pathway ID (Panther)	P00002