ProRule section of PROSITE is constituted of manually created rules that increase the discriminatory power of PROSITE motifs (generally profiles) by providing additional information about functionally and/or structurally critical amino acids and can automatically generate annotation based on PROSITE motifs in the UniProtKB/Swiss-Prot format. Each ProRule is defined in the UniRule format.
|EDAM topic||Protein functional sites|
|EDAM topic||Sequence motifs|
|EDAM topic||Sequence profiles and HMMs|